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Systems biology versus molecular biology
Systems biology and molecular biology can answer the same question in quite different ways, and frequently the answers given by one sub-discipline seem no answer at all to the other. For many molecular biologists, a systemslevel explanation leaves them feeling that, until the underlying molecular mechanisms are known, the approach is hopelessly superficial. For systems biologists, on the other ...
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In the history of biology, the early 1950s to the mid-1960s represent a period of landmark discoveries that led to the establishment of a new science named Molecular Biology. The discovery of the double helical structure of DNA byWatson and Crick in 1953 facilitated the formulation of specific questions related to the hottest questions of the time, gene replication and expression. Many ambitiou...
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In the postgenomic era, the large-scale data, such as genome sequences, mRNA sequences, and protein sequences, increase rapidly. It is desired to develop the computational approaches that can derive and analyze useful information from them to promote the development of biomedicine and drug design. Meanwhile, in order to understand how protein-protein interactions and other complex interactions ...
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The shock of wasabi, the dreadful pain of a toothache , even the itch of a poison ivy rash—blame it on a TRP channel. The transient receptor potential (TRP) channels trigger pain and inflammation in sensory neurons throughout the body, but these six families of cation channels are expressed in almost every type of cell in humans. This Molecular Biology Select summarizes recent studies that high...
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ژورنال
عنوان ژورنال: Nature
سال: 1982
ISSN: 0028-0836,1476-4687
DOI: 10.1038/295006b0